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Amplification of nuclear aldolase A in mouse cell mutants resistant to Hoechst 33342.

Biochemical and biophysical research communications - 19 Mar 2004

Satou Wataru, Tanimoto Hiroshi, Ukekawa Ryo, Fujii Michihiko, Ayusawa Dai

Abstract excerpt

5-Bromodeoxyuridine (BrdU) induces a phenomenon similar to cellular senescence in mammalian cells. AT-binding ligands such as Hoechst 33258 synergistically potentiate the effect of BrdU. We isolated mouse FM3A cell mutants resistant to Hoechst 33342 and characterized two highly resistant mutants. Two-dimensional gel electrophoresis followed by peptides sequence tags revealed that nuclear aldolase A was markedly...

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Identifiers

PMID: 14985089
DOI: 10.1016/j.bbrc.2004.01.142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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