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Article

Cell viability and secretion of active proteins in Schizosaccharomyces pombe do not require the chaperone function of calnexin.

The Biochemical journal - 1 Jun 2004

Maréchal Alexandre, Tanguay Pierre-Luc, Callejo Mario, Guérin Renée, Boileau Guy, Rokeach Luis A

Abstract excerpt

Folding of newly synthesized proteins within the ER (endoplasmic reticulum) is a rate-limiting step in protein secretion. Thus ER molecular chaperones and foldases have a major impact in determining the rate and yield of these crucial cellular processes. Calnexin is a key ER chaperone implicated in the folding, retention and targeting for degradation of proteins that go through the secretory pathway. Calnexin...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 14984369
DOI: 10.1042/BJ20031546
PMCID: PMC1224181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Cell viability and secretion of active proteins in Schizosaccharomyces pombe do not require the chaperone function of calnexin.PMID 14984369Read ↗

The calnexin-independent state does not compensate for all calnexin functions in Schizosaccharomyces pombe.Semantic proximity Read ↗

A non-chromosomal factor allows viability of Schizosaccharomyces pombe lacking the essential chaperone calnexin.Semantic proximity Read ↗

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Calnexin is involved in apoptosis induced by endoplasmic reticulum stress in the fission yeast.Semantic proximity Read ↗

Stress tolerance of misfolded carboxypeptidase Y requires maintenance of protein trafficking and degradative pathways.Semantic proximity Read ↗

The UDP-Glc:Glycoprotein glucosyltransferase is essential for Schizosaccharomyces pombe viability under conditions of extreme endoplasmic reticulum stress.Semantic proximity Read ↗

Isolation and characterisation of a calnexin homologue, clxA, from Aspergillus niger.Semantic proximity Read ↗

Vacuolar carboxypeptidase Y of Saccharomyces cerevisiae is glycosylated, sorted and matured in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

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Identification of the essential EPE1 gene involved in retention of secreted proteins on the cell surface of Saccharomyces cerevisiae cells.Semantic proximity Read ↗

Contrasting Functions of Calreticulin and Calnexin in Glycoprotein Folding and ER Quality ControlSemantic proximity Read ↗

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