Article
The UDP-Glc:Glycoprotein glucosyltransferase is essential for Schizosaccharomyces pombe viability under conditions of extreme endoplasmic reticulum stress.
The Journal of cell biology - 2 Nov 1998
Fanchiotti S, Fernández F, D'Alessio C, Parodi A J
Abstract excerpt
Interaction of monoglucosylated oligosaccharides with ER lectins (calnexin and/or calreticulin) facilitates glycoprotein folding but this interaction is not essential for cell viability under normal conditions. We obtained two distinct single Schizosaccharomyces pombe mutants deficient in either...
Topics
- Carbohydrate Sequence
- Endoplasmic Reticulum
- Glucosyltransferases
- Glycosylation
- Molecular Sequence Data
- Mutagenesis
- Oligosaccharides
- Phenotype
- Protein Folding
- Schizosaccharomyces
- Temperature