Article
The calnexin-independent state does not compensate for all calnexin functions in Schizosaccharomyces pombe.
FEMS yeast research - 1 Mar 2007
Turcotte Cynthia, Roux Antoine, Beauregard Pascale B, Guérin Renée, Sénéchal Patrick, Hajjar Fadi, Rokeach Luis A
Abstract excerpt
In the yeast Schizosaccharomyces pombe, the molecular chaperone calnexin (Cnx1p) has been shown to be essential for viability. However, we recently reported that, under certain circumstances, S. pombe cells are able to survive in the absence of calnexin/Cnx1p, indicating that an inducible pathway can complement the calnexin/Cnx1p essential function(s). This calnexin-independent state (Cin) is transmitted by a...
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