Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A non-chromosomal factor allows viability of Schizosaccharomyces pombe lacking the essential chaperone calnexin.

Journal of cell science - 29 Feb 2004

Collin Philippe, Beauregard Pascale B, Elagöz Aram, Rokeach Luis A

Abstract excerpt

Calnexin is a molecular chaperone playing key roles in protein folding and the quality control of this process in the endoplasmic reticulum. We, and others, have previously demonstrated that cnx1(+), the gene encoding the calnexin homologue in Schizosaccharomyces pombe, is essential for viability. We show that a particular cnx1 mutant induces a novel mechanism allowing the survival of S. pombe cells in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calnexin
Share to Cell Survival
Share to Chromosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endoplasmic Reticulum

Share to Glucosyltransferases

Share to Protein Folding

Share to Schizosaccharomyces

Share to Schizosaccharomyces pombe Proteins

Source

Identifiers

PMID: 14963023
DOI: 10.1242/jcs.00943

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A non-chromosomal factor allows viability of Schizosaccharomyces pombe lacking the essential chaperone calnexin.PMID 14963023Read ↗

The calnexin-independent state does not compensate for all calnexin functions in Schizosaccharomyces pombe.Semantic proximity Read ↗

A nucleolar protein allows viability in the absence of the essential ER-residing molecular chaperone calnexin.Semantic proximity Read ↗

The epigenetic calnexin-independent state is induced in response to environmental changes.Semantic proximity Read ↗

Cell viability and secretion of active proteins in Schizosaccharomyces pombe do not require the chaperone function of calnexin.Semantic proximity Read ↗

Calnexin is involved in apoptosis induced by endoplasmic reticulum stress in the fission yeast.Semantic proximity Read ↗

Calnexin regulates apoptosis induced by inositol starvation in fission yeast.Semantic proximity Read ↗

Schizosaccharomyces pombe cells lacking the Ran-binding protein Hba1 show a multidrug resistance phenotype due to constitutive nuclear accumulation of Pap1.Semantic proximity Read ↗

The UDP-Glc:Glycoprotein glucosyltransferase is essential for Schizosaccharomyces pombe viability under conditions of extreme endoplasmic reticulum stress.Semantic proximity Read ↗

Characterization of cwl1+, a gene from Schizosaccharomyces pombe whose overexpression causes cell lysis.Semantic proximity Read ↗

Identification of the fnx1+ and fnx2+ genes for vacuolar amino acid transporters in Schizosaccharomyces pombe.Semantic proximity Read ↗

Identification of the genes encoding the cytosolic translation release factors from Podospora anserina and analysis of their role during the life cycle.Semantic proximity Read ↗

Isolation and characterization of Schizosaccharomyces pombe mutants lacking aminopeptidase activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.