Article
FAS (CD95) mutations are rare in gastric MALT lymphoma but occur more frequently in primary gastric diffuse large B-cell lymphoma.
The American journal of pathology - 1 Mar 2004
Wohlfart Sabine, Sebinger David, Gruber Petra, Buch Judith, Polgar Doris, Krupitza Georg, Rosner Margit, Hengstschläger Markus, Raderer Markus, Chott Andreas, Müllauer Leonhard
Abstract excerpt
A loss of FAS (CD95) function has been proposed to constitute an important step in early mucosa-associated lymphoid tissue (MALT) lymphoma development and FAS mutations have been recognized in malignant lymphomas, in particular at extranodal sites. Since primary gastric lymphomas frequently exhibit resistance to FAS-mediated apoptosis, we investigated whether FAS is mutated in 18 gastric MALT lymphomas and 28...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
