Article
Infrequent somatic Fas mutations but no evidence of Bcl10 mutations or t(11;18) in primary cutaneous MALT-type lymphoma.
The Journal of pathology - 1 Sept 2003
Grønbaek Kirsten, Ralfkiaer Elisabeth, Kalla Jörg, Skovgaard Gunhild L, Guldberg Per
Abstract excerpt
Genetic alterations that allow tumour cells to evade apoptosis have recently been identified as key features of extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue type (MALT-type lymphoma). The t(11;18), which produces the putative anti-apoptotic fusion protein API2-MALT1, has been identified in a large proportion of extracutaneous MALT-type lymphomas and a smaller fraction of tumours harbour...
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