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Article

Genetic analysis of candidate loci in non-syndromic cleft lip families from Antioquia-Colombia and Ohio.

American journal of medical genetics. Part A - 1 Mar 2004

Moreno Lina M, Arcos-Burgos Mauricio, Marazita Mary L, Krahn Katherine, Maher Brion S, Cooper Margaret E, Valencia-Ramirez Consuelo R, Lidral Andrew C

Abstract excerpt

Non-syndromic cleft lip with or without cleft palate (CL/P) is a genetically complex birth defect, with a prevalence from 1/500 to 1/1,000 live births. Evidence from linkage and linkage disequilibrium studies is contradictory suggesting that heterogeneity between study populations may exist. A recent report of a genome widescan in 92 sib pairs from the United Kingdom revealed suggestive linkage to 10 loci...

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Source

Identifiers

PMID: 14981713
DOI: 10.1002/ajmg.a.20425

Genes

TGFA
NPL
MSX1
RARA
TGFB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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