Article
Replication analysis of 15 susceptibility loci for nonsyndromic cleft lip with or without cleft palate in an italian population.
Birth defects research. Part A, Clinical and molecular teratology - 1 Feb 2016
Cura Francesca, Böhmer Anne C, Klamt Johanna, Schünke Hannah, Scapoli Luca, Martinelli Marcella, Carinci Francesco, Nöthen Markus M, Knapp Michael, Ludwig Kerstin U, Mangold Elisabeth
Abstract excerpt
BACKGROUND: Nonsyndromic cleft lip with or without cleft palate (nsCL/P) is one of the most common congenital malformations in humans. Its average global incidence is 1.7 per 1000 live births, with wide variation according to geographical location and ethnicity. Its etiology involves both genetic and environmental factors. The aim of the present study was to confirm genetic association of a selection of 15...
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