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Article

Association of candidate genes with nonsyndromic clefts in Honduran and Colombian populations.

The Laryngoscope - 1 Sept 2012

Lennon Christen J, Birkeland Andrew C, Nuñez José Arturo Pacheco, Su Gloria H, Lanzano Patricia, Guzman Edwin, Celis Katrina, Eisig Sidney B, Hoffman David, Rendon Maria Teresa Guerra, Ostos Henry, Chung Wendy K, Haddad Joseph

Abstract excerpt

OBJECTIVES/HYPOTHESIS: Orofacial clefts are the most common craniofacial birth defects in humans, with the majority of orofacial clefts occurring as nonsyndromic cleft lip with or without cleft palate (NSCLP). We previously demonstrated associations between single-nucleotide polymorphisms (SNPs) in the IRF6 gene and NSCLP in the Honduran population. Here we investigated other candidate genes and chromosomal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22753311
DOI: 10.1002/lary.23394

Genes

ABCA4
MAFB
FOXE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of candidate genes with nonsyndromic clefts in Honduran and Colombian populations.PMID 22753311Read ↗

Association of common variants, not rare mutations, in IRF6 with nonsyndromic clefts in a Honduran population.Semantic proximity Read ↗

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Potential genetic markers for nonsyndromic oral clefts in the Brazilian population: A systematic review and meta-analysis.Semantic proximity Read ↗

The association between interferon regulatory factor 6 (IRF6) and nonsyndromic cleft lip with or without cleft palate in a Honduran population.Semantic proximity Read ↗

Genome-wide association study of multiethnic nonsyndromic orofacial cleft families identifies novel loci specific to family and phenotypic subtypes.Semantic proximity Read ↗

Identifying Genetic Sources of Phenotypic Heterogeneity in Orofacial Clefts by Targeted Sequencing.Semantic proximity Read ↗

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Genome-wide association study of multiethnic non-syndromic orofacial cleft families identifies novel loci specific to family and phenotypic subtypesSemantic proximity Read ↗

Evaluation of genome-wide association signals for nonsyndromic cleft lip with or without cleft palate in a multiethnic Brazilian population.Semantic proximity Read ↗

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