Article
Evaluating eight newly identified susceptibility loci for nonsyndromic cleft lip with or without cleft palate in a Mesoamerican population.
Birth defects research. Part A, Clinical and molecular teratology - 1 Jan 2014
Ludwig Kerstin U, Wahle Philipp, Reutter Heiko, Paredes-Zenteno Mario, Muñoz-Jimenez Sergio G, Ortiz-Lopez Rocio, Böhmer Anne C, Tessmann Peter, Nowak Stefanie, Nöthen Markus M, Knapp Michael, Rojas-Martinez Augusto, Mangold Elisabeth
Abstract excerpt
BACKGROUND: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is among the most frequently occurring congenital malformations worldwide. The number of genetic loci identified as being involved in NSCL/P etiology was recently increased by a large genome-wide meta-analysis of European and Asian samples. This meta-analysis confirmed all six previously recognized genetic susceptibility loci and identified...
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