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Article

Discovery of candidate genes for nonsyndromic cleft lip palate through genome-wide linkage analysis of large extended families in the Malay population.

BMC genetics - 11 Feb 2016

Mohamad Shah Nurul Syazana, Salahshourifar Iman, Sulong Sarina, Wan Sulaiman Wan Azman, Halim Ahmad Sukari

Abstract excerpt

BACKGROUND: Nonsyndromic orofacial clefts are one of the most common birth defects worldwide. It occurs as a result of genetic or environmental factors. This study investigates the genetic contribution to nonsyndromic cleft lip and/or palate through the analysis of family pedigrees. Candidate genes associated with the condition were identified from large extended families from the Malay population. RESULTS: A...

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Source

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Identifiers

PMID: 26868259
DOI: 10.1186/s12863-016-0345-x
PMCID: PMC4751652

Genes

NPL
FOXG1
FOXP2
HECTD1
SATB2
TOX3

Provenance

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Discovery of candidate genes for nonsyndromic cleft lip palate through genome-wide linkage analysis of large extended families in the Malay population.PMID 26868259Read ↗

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