Article
Targeted scan of fifteen regions for nonsyndromic cleft lip and palate in Filipino families.
American journal of medical genetics. Part A - 15 Feb 2004
Schultz R E, Cooper M E, Daack-Hirsch S, Shi M, Nepomucena B, Graf K A, O'Brien E K, O'Brien S E, Marazita M L, Murray J C
Abstract excerpt
Cleft lip with or without cleft palate (CL/P) is a congenital anomaly with variable birth prevalence based on geographic origins, with the highest rates commonly found in Asian populations. About 70% of cases are nonsyndromic (NS), in which the affected individual has no other abnormalities. NS CL/P is a complex disorder with genetic and environmental effects and no specific genetic loci yet confirmed. Fifteen...
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