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Article

Coincidence of genetic loci for plasma cholesterol levels and obesity in a multifactorial mouse model.

The Journal of clinical investigation - 1 Aug 1993

Warden C H, Fisler J S, Pace M J, Svenson K L, Lusis A J

Abstract excerpt

We have examined backcross progeny derived from a cross of Mus spretus with C57BL/6J, that range from 1 to 50% carcass lipid (n = 215), and from 22 to 130 mg/dl plasma total cholesterol (n = 238). Statistical analysis revealed that distal mouse chromosome 7 exhibits significant linkage both to plasma total cholesterol (likelihood of the odds [LOD] 5.8) and to carcass lipid (LOD 3.8). A locus on chromosome 6 also...

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Identifiers

PMID: 8349816
DOI: 10.1172/JCI116649
PMCID: PMC294913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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