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Article

Identification and characterization of a human smad3 splicing variant lacking part of the linker region.

Gene - 3 Mar 2004

Kjellman Christian, Honeth Gabriella, Järnum Sofia, Lindvall Magnus, Darabi Anna, Nilsson Ingar, Edvardsen Klaus, Salford Leif G, Widegren Bengt

Abstract excerpt

Smad3 is one of the signal transducers that are activated in response to transforming growth factor-beta (TGF-beta). We have identified and characterized a splicing variant of smad3. The splicing variant (smad3-Delta3) lacks exon 3 resulting in a truncated linker region. We could detect mRNA expression of smad3-Delta3 in all investigated human tissues. Real-time PCR analyses demonstrated that the fraction of...

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Identifiers

PMID: 14980711
DOI: 10.1016/j.gene.2003.11.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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