Smad2 linker region phosphorylation is an autonomous cell signalling pathway: Implications for multiple disease pathologies

Abstract excerpt

This review will cover the signalling pathways leading to the phosphorylation of the Smad linker region independent of Smad carboxy terminal phosphorylation. Characterising Smad linker region as a signalling pathway in its own right will encourage comprehensive signalling studies to provide solutions for successful discovery and exploitation of drug targets. The review describes Smad transcription factor...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetic factors in colorectal cancer
• Share to Pancreatic and Hepatic Oncology Research
• Share to TGF-β signaling in diseases