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Article

Proteasomal ATPases link ubiquitylation of histone H2B to methylation of histone H3.

Molecular cell - 13 Feb 2004

Ezhkova Elena, Tansey William P

Abstract excerpt

In Saccharomyces cerevisiae, methylation of histone H3 at active genes is an epigenetic mark that distinguishes active from silent chromatin and functions as a short-term "memory" of recent transcription. Methylation of H3 at lysine residues K4 and K79 depends on ubiquitylation of histone H2B, bu...

Topics

Adenosine Triphosphatases
Cells, Cultured
Cysteine Endopeptidases
Epigenesis, Genetic
Histones
Methylation
Multienzyme Complexes
Mutation
Proteasome Endopeptidase Complex
RNA Interference
Repressor Proteins
Saccharomyces cerevisiae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae Proteins

Transcriptional Activation

Ubiquitin

Source

Identifiers

PMID: 14967150
DOI: 10.1016/s1097-2765(04)00026-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-14967150-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Proteasomal ATPases link ubiquitylation of histone H2B to methylation of histone H3.PMID 14967150Read ↗

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