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Article

[Mutation Frequencies in RNAi Targets in HIV-1 Genomes Obtained from Blood Plasma of Patients Receiving Anti-Retroviral Therapy].

Molekuliarnaia biologiia - 1 Jan 2000

Kretova O V, Gorbacheva M A, Fedoseeva D M, Kravatskya Y V, Chechetkin V R, Tchurikov N A

Abstract excerpt

Gene therapy for AIDS based on RNA interference (RNAi) is currently looked upon as a promising alternative to conventional antiretroviral chemotherapy. The high variability of HIV-1 is the main challenge in developing new approaches to AIDS therapy. To date, about 18 million HIV-1 infected individuals receive antiretroviral therapy worldwide. As of 2017, about 44% of individuals with AIDS received antiretroviral...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30113024
DOI: 10.1134/S0026898418040110

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