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Article

Use of single-cycle analysis to study rates and mechanisms of retroviral mutation.

Methods (San Diego, Calif.) - 1 Aug 1997

Yu H, Jetzt A E, Dougherty J P

Abstract excerpt

Retroviruses evolve at rapid rates. This allows them to escape immune surveillance, thwarts vaccine development, and leads to rapid emergence of drug-resistant virus. Information regarding the retroviral mutation rates and the underlying mechanisms of mutagenesis will undoubtedly expedite the development of strategies to combat retroviral-mediated diseases. In this review, we discuss how the unique retroviral...

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Identifiers

PMID: 9245613
DOI: 10.1006/meth.1997.0486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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