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Article

Differential role of the loop region between helices H6 and H7 within the orphan nuclear receptors small heterodimer partner and DAX-1.

Molecular endocrinology (Baltimore, Md.) - 1 May 2004

Park Yun-Yong, Kim Han-Jong, Kim Joon-Young, Kim Mi-Young, Song Kwang-Hoon, Cheol Park Ki, Yu Kang-Yeol, Shong Minho, Kim Kyoung-Hee, Choi Hueng-Sik

Abstract excerpt

The orphan nuclear receptors small heterodimer partner (SHP) and dosage-sensitive sex-reversal adrenal hypoplasia congenital (AHC) critical region on the X chromosome gene 1 (DAX-1) contain extra amino acids between helices H6 and H7 of LBD, and here we investigated a possible role of these additional amino acids. Transient transfection assay demonstrated that, in contrast to wild type, in mutant SHP Delta128-139...

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Identifiers

PMID: 14963109
DOI: 10.1210/me.2003-0339

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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