Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP.

EMBO reports - 1 May 2002

Båvner Ann, Johansson Lotta, Toresson Gudrun, Gustafsson Jan-Ake, Treuter Eckardt

Abstract excerpt

SHP (short heterodimer partner, NROB2) is an atypical orphan member of the mammalian nuclear receptor family that consists only of a putative ligand-binding domain and thus cannot bind DNA. Instead, SHP acts as a transcriptional coregulator by inhibiting the activity of various nuclear receptors...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetyltransferases
Share to Adenovirus E1A Proteins
Share to COS Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histones

Share to Intracellular Signaling Peptides and Proteins

Share to Receptors, Cytoplasmic and Nuclear

Share to Sequence Analysis, Protein

Share to Two-Hybrid System Techniques

Source

Open in PubMed Open full text

Identifiers

PMID: 11964378
DOI: 10.1093/embo-reports/kvf087
PMCID: PMC1084100

Genes

EID1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11964378-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP.PMID 11964378Read ↗

The orphan nuclear receptor SHP utilizes conserved LXXLL-related motifs for interactions with ligand-activated estrogen receptors.Semantic proximity Read ↗

Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD.Semantic proximity Read ↗

Differential role of the loop region between helices H6 and H7 within the orphan nuclear receptors small heterodimer partner and DAX-1.Semantic proximity Read ↗

Glucocorticoid signaling is perturbed by the atypical orphan receptor and corepressor SHP.Semantic proximity Read ↗

Analysis of the structure and function of the transcriptional coregulator HOP.Semantic proximity Read ↗

Dual Mechanisms for Repression of the Monomeric Orphan Receptor Liver Receptor Homologous Protein-1 by the Orphan Small Heterodimer PartnerSemantic proximity Read ↗

Synergistic regulation of the mouse orphan nuclear receptor SHP gene promoter by CLOCK-BMAL1 and LRH-1.Semantic proximity Read ↗

LXXLL motifs and AF-2 domain mediate SHP (NR0B2) homodimerization and DAX1 (NR0B1)-DAX1A heterodimerization.Semantic proximity Read ↗

Global Gene Repression by the Steroid Receptor Coactivator SRC-1 Promotes OncogenesisSemantic proximity Read ↗

Co-activator candidate interactions for orphan nuclear receptor NR2E1.Semantic proximity Read ↗

The cell adhesion molecule echinoid functions as a tumor suppressor and upstream regulator of the Hippo signaling pathway.Semantic proximity Read ↗

Role of nuclear receptor SHP in metabolism and cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.