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Article

DAX1: Increasing complexity in the roles of this novel nuclear receptor.

Molecular and cellular endocrinology - 1 Feb 2007

McCabe Edward R B

Abstract excerpt

DAX1 (NR0B1) is a nuclear receptor with a characteristic C-terminal ligand binding domain, but an atypical DNA binding domain. Mutations in the DAX1 gene cause adrenal hypoplasia congenita (AHC) establishing its biological importance. Recent studies highlight the complexities of DAX1 regulation and function. There is considerable phenotypic variability in AHC suggesting the existence of DAX1 modifier genes and...

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Identifiers

PMID: 17210221
DOI: 10.1016/j.mce.2006.12.017
PMCID: PMC1847396

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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