Article
Genomic sequence of the DAX1 gene: an orphan nuclear receptor responsible for X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism.
The Journal of clinical endocrinology and metabolism - 1 Jul 1996
Guo W, Burris T P, Zhang Y H, Huang B L, Mason J, Copeland K C, Kupfer S R, Pagon R A, McCabe E R
Abstract excerpt
The gene responsible for X-linked adrenal hypoplasia congenita, DAX1, encodes a member of the nuclear hormone receptor superfamily. We sequenced 8851 bp that contained the DAX1 genomic region. The DAX gene was composed of two exons and one 3.4-kilobase intron. Putative TATA and GC boxes and a putative steroidogenic factor 1 response element were present in the 5'-flanking region. Two potentially polymorphic short...
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