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Article

Calnexin regulates apoptosis induced by inositol starvation in fission yeast.

PloS one - 16 Jul 2009

Guérin Renée, Beauregard Pascale B, Leroux Alexandre, Rokeach Luis A

Abstract excerpt

Inositol is a precursor of numerous phospholipids and signalling molecules essential for the cell. Schizosaccharomyces pombe is naturally auxotroph for inositol as its genome does not have a homologue of the INO1 gene encoding inositol-1-phosphate synthase, the enzyme responsible for inositol biosynthesis. In this work, we demonstrate that inositol starvation in S. pombe causes cell death with apoptotic features....

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Identifiers

PMID: 19606215
DOI: 10.1371/journal.pone.0006244
PMCID: PMC2705804

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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