Article
Study of CXCL9-11 gene polymorphisms in liver fibrosis among patients with chronic hepatitis C.
Pathogens and disease - 20 Mar 2021
Magri Mariana Cavalheiro, Alvarez Maria Stella Montanha, Iogi Anny Ayumi, Alves Grayce Mendes, Manchiero Caroline, Dantas Bianca Peixoto, Prata Thamiris Vaz Gago, Nunes Arielle Karen da Silva, Tengan Fátima Mitiko
Abstract excerpt
Several factors are associated with the progression of chronic hepatitis C: comorbidities, lifestyle, and pathogenic factors, including immune response, apoptosis and heredity. Single nucleotide polymorphisms (SNPs) in the PNPLA3 and TM6SF2 genes are more widely studied genetic risk factors, while CXCL9-11 chemokines produced by hepatocytes in the process of infection are less well studied. Our aim was to...
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