Article
Impact of IL-27p28 (rs153109) and TNF-α (rs1800629) Genetic Polymorphisms on the Progression of HCV Infection in Egyptian Patients.
Immunological investigations - 1 Apr 2019
Tharwat Ebram, Gad Gamal F M, Nazmy Maiiada H, Mohamed Hala I, Hamza Nouran, Wahid Ahmed, Ibrahim Ahmed R N
Abstract excerpt
BACKGROUND: Hepatitis C virus (HCV) is a universal health problem. HCV infection may proceed to liver fibrosis, cirrhosis, and eventually hepatocellular carcinoma (HCC). The latest is the third leading global cause of cancer-related mortality. Cytokines including IL-27 and TNF-α play a major role as a link between innate and adaptive immunity which in turn deduct the outcome of HCV infection. AIM: The present...
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