Article
Analysis of R-Ras signalling pathways.
Journal of cell science - 1 Apr 2001
Self A J, Caron E, Paterson H F, Hall A
Abstract excerpt
R-Ras has a high degree of sequence homology to Ras and to other members of the Ras subfamily including Rap, TC21 and M-Ras. Activated versions of Ras and TC21 are highly transforming in a variety of cell lines and mutated forms of both proteins have been found in human tumours. R-Ras interacts with many of the same proteins as Ras and TC21, including c-Raf1, and can induce transformed foci, although this...
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