Article
Expression of alpha and beta subunit isoforms of Na,K-ATPase in the mouse inner ear and changes with mutations at the Wv or Sld loci.
Hearing research - 1 Jul 1994
Schulte B A, Steel K P
Abstract excerpt
Mice homozygous for mutations at the viable dominant spotting (Wv) and Steel-dickie (Sld) loci exhibit a similar phenotype which includes deafness. The auditory dysfunction derives from failure of the stria vascularis to develop normally and to generate a high positive endocochlear potential (EP)...
Topics
- Animals
- Cochlea
- Female
- Immunohistochemistry
- Isoenzymes
- Male
- Mice
- Minor Histocompatibility Loci
- Mutation
- Sodium-Potassium-Exchanging ATPase
- Stria Vascularis