Article
Dysgenesis of melanocytes and cochlear dysfunction in mutant microphthalmia (mi) mice.
Hearing research - 1 Oct 1994
Motohashi H, Hozawa K, Oshima T, Takeuchi T, Takasaka T
Abstract excerpt
In order to evaluate the cytological homology of intermediate cells and melanocytes, and to investigate the function of melanocytes in the inner ear, hearing acuity and cochlear pathology were studied in three strains of mice, namely, wild type mice (+/+), albino mice without melanin (c2J/c2J), and microphthalmia mice with no melanocytes (mibw/mibw). Our histochemical data indicated that intermediate cells showed...
Topics
- Animals
- Auditory Threshold
- Calcium-Transporting ATPases
- Cochlea
- Dihydroxyphenylalanine
- Evoked Potentials, Auditory, Brain Stem
- Hearing Loss, Sensorineural
- Immunohistochemistry
- Melanins
- Melanocytes
- Mice
