Article
Light (Blt), a mutation that causes melanocyte death, affects stria vascularis function in the mouse inner ear.
Pigment cell research - 1 Aug 1993
Cable J, Jackson I J, Steel K P
Abstract excerpt
The Light mutation (Blt) is a dominant allele of the b-locus on mouse chromosome 4 which causes progressive dilution of coat colour. Melanocytes within the hair follicles of mutant mice develop normally but later degenerate, due to the accumulation of a toxic product, so that the hair becomes lighter with age. Previous studies on W-locus spotting mutants, from which melanocytes are absent, have shown that...
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