Light (Blt), a mutation that causes melanocyte death, affects stria vascularis function in the mouse inner ear.

doi:10.1111/j.1600-0749.1993.tb00605.x

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Article

Light (Blt), a mutation that causes melanocyte death, affects stria vascularis function in the mouse inner ear.

Pigment cell research - 1 Aug 1993

Cable J, Jackson I J, Steel K P

Abstract excerpt

The Light mutation (Blt) is a dominant allele of the b-locus on mouse chromosome 4 which causes progressive dilution of coat colour. Melanocytes within the hair follicles of mutant mice develop normally but later degenerate, due to the accumulation of a toxic product, so that the hair becomes lig...

Topics

Aging
Alleles
Animals
Atrophy
Base Sequence
Cell Death
Ear, Inner
Hair Color
Heterozygote
Homozygote
Melanocytes
Mice
Molecular Sequence Data
Mutation
Skin
Skin Physiological Phenomena
Stria Vascularis

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