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Article

RASSF1A methylation indicates a poor prognosis in hepatoblastoma patients.

Pediatric surgery international - 1 Nov 2013

Honda Shohei, Miyagi Hisayuki, Suzuki Hiromu, Minato Masashi, Haruta Masayuki, Kaneko Yasuhiko, Hatanaka Kanako C, Hiyama Eiso, Kamijo Takehiko, Okada Tadao, Taketomi Akinobu

Abstract excerpt

PURPOSE: The RAS association domain family protein 1 (RASSF1A) is known to be frequently inactivated by promoter hypermethylation in cancers. This study investigated the association of RASSF1A methylation with clinical outcomes in hepatoblastoma patients and whether it is correlated with the histological phenotype of hepatoblastoma tumors. METHODS: Seventy-four hepatoblastoma tumors were obtained from patients...

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Share to Biomarkers, Tumor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

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Share to Liver Neoplasms

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Share to Promoter Regions, Genetic

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 23989600
DOI: 10.1007/s00383-013-3371-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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