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Article

The big brain gene of Drosophila functions to control the number of neuronal precursors in the peripheral nervous system.

Development (Cambridge, England) - 1 Sept 1992

Rao Y, Bodmer R, Jan L Y, Jan Y N

Abstract excerpt

big brain (bib) is one of the six known zygotic neurogenic genes involved in the decision of an ectodermal cell to take on the neurogenic or the epidermogenic cell fate. Previous studies suggest that bib functions in a pathway separate from the one involving Notch and other known neurogenic genes...

Topics

Animals
Cell Differentiation
Drosophila
Drosophila Proteins
Embryo, Nonmammalian
Genes, Insect
Membrane Proteins
Mutation
Neurons
Peripheral Nerves
Phenotype
Stem Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1483394
DOI: 10.1242/dev.116.1.31

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1483394-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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