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Article

Similarity of the product of the Drosophila neurogenic gene big brain to transmembrane channel proteins.

Nature - 10 May 1990

Rao Y, Jan L Y, Jan Y N

Abstract excerpt

Cells in the neurogenic region of Drosophila embryos are initially bipotential; they can become either neuroblasts or epidermoblasts. Cell-cell interaction seems to play an important part in this developmental decision, which involves the function of a group of genes (the neurogenic genes). Loss-of-function mutations in any of the neurogenic genes result in nervous system hyperplasia and epidermal hypoplasia. Of...

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PMID: 1692392
DOI: 10.1038/345163a0

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