Similarity of the product of the Drosophila neurogenic gene big brain to transmembrane channel proteins.

doi:10.1038/345163a0

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Article

Similarity of the product of the Drosophila neurogenic gene big brain to transmembrane channel proteins.

Nature - 10 May 1990

Rao Y, Jan L Y, Jan Y N

Abstract excerpt

Cells in the neurogenic region of Drosophila embryos are initially bipotential; they can become either neuroblasts or epidermoblasts. Cell-cell interaction seems to play an important part in this developmental decision, which involves the function of a group of genes (the neurogenic genes). Loss-of-function mutations in any of the neurogenic genes result in nervous system hyperplasia and epidermal hypoplasia. Of...

Topics

Amino Acid Sequence
Animals
Base Sequence
Blastoderm
Brain
Cell Membrane
Cloning, Molecular
DNA
Drosophila
Ectoderm
Gene Expression
Genes, Lethal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ion Channels

Mesoderm

Molecular Sequence Data

Mutation

Nervous System

Nucleic Acid Hybridization

Source

Open in PubMed

Identifiers

PMID: 1692392
DOI: 10.1038/345163a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1692392-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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