Article
Worniu, a Snail family zinc-finger protein, is required for brain development in Drosophila.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Oct 2004
Ashraf Shovon I, Ganguly Atish, Roote John, Ip Y Tony
Abstract excerpt
The Snail family of zinc-finger transcriptional repressors is essential for morphogenetic cell movements, mesoderm formation, and neurogenesis during embryonic development. These proteins also control cell cycle, cell death, and cancer progression. In Drosophila, three members of this protein family, Snail, Escargot, and Worniu, have essential but redundant functions in asymmetric cell division of neuroblasts. In...
Topics
- Animals
- Animals, Genetically Modified
- Brain
- Drosophila Proteins
- Drosophila melanogaster
- In Situ Hybridization
- Larva
- Phenotype
- RNA Interference
- Snail Family Transcription Factors
