Article
The Drosophila neurogenic gene big brain, which encodes a membrane-associated protein, acts cell autonomously and can act synergistically with Notch and Delta.
Development (Cambridge, England) - 1 Oct 1997
Doherty D, Jan L Y, Jan Y N
Abstract excerpt
In the developing nervous system of Drosophila, cells in each proneural cluster choose between neural and epidermal cell fates. The neurogenic genes mediate the cell-cell communication process whereby one cell adopts the neural cell fate and prevents other cells in the cluster from becoming neura...
Topics
- Amino Acid Sequence
- Animals
- Antibodies
- Cloning, Molecular
- Drosophila
- Drosophila Proteins
- Embryo, Nonmammalian
- Embryonic Induction
- Epidermal Cells
- Epidermis
- Genes, Insect
- Immunohistochemistry
- Intracellular Signaling Peptides and Proteins
- Membrane Proteins
- Microscopy, Immunoelectron
- Molecular Sequence Data
- Mosaicism
- Nervous System