Article
P-element mutations affecting embryonic peripheral nervous system development in Drosophila melanogaster.
Genetics - 1 Apr 1995
Kania A, Salzberg A, Bhat M, D'Evelyn D, He Y, Kiss I, Bellen H J
Abstract excerpt
The Drosophila embryonic peripheral nervous system (PNS) is an excellent model system to study the molecular mechanisms governing neural development. To identify genes controlling PNS development, we screened 2000 lethal P-element insertion strains. The PNS of mutant embryos was examined using the neural specific marker MAb 22C10, and 92 mutant strains were retained for further analysis. Genetic and cytological...
Topics
- Animals
- Chromosome Mapping
- DNA Transposable Elements
- Drosophila melanogaster
- Mutation
- Neurons
- Peripheral Nervous System
- Phenotype