Article
Glucocorticoid sensitivity is determined by a specific glucocorticoid receptor haplotype.
The Journal of clinical endocrinology and metabolism - 1 Feb 2004
Stevens Adam, Ray David W, Zeggini Eleftheria, John Sally, Richards Helen L, Griffiths Christopher E M, Donn Rachelle
Abstract excerpt
Differences in glucocorticoid (GC) sensitivity may underlie both common diseases (e.g. hypertension) and variability in response to treatment with GCs (e.g. asthma). We tested the potential involvement of the GC receptor (GR) gene in mediating GC sensitivity using haplotype analysis and a low-dos...
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