Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Current concepts in glucocorticoid resistance.

Steroids - 1 Sept 2012

Yang Nan, Ray David W, Matthews Laura C

Abstract excerpt

Glucocorticoids (GCs) are the most potent anti-inflammatory agents known. A major factor limiting their clinical use is the wide variation in responsiveness to therapy. The high doses of GC required for less responsive patients means a high risk of developing very serious side effects. Variation in sensitivity between individuals can be due to a number of factors. Congenital, generalized GC resistance is very...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Inflammatory Agents
Share to Cellular Microenvironment
Share to Chronic Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance

Share to Glucocorticoids

Share to Hypoxia

Share to Oxidative Stress

Share to Receptors, Glucocorticoid

Source

Identifiers

PMID: 22728894
DOI: 10.1016/j.steroids.2012.05.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Current concepts in glucocorticoid resistance.PMID 22728894Read ↗

Primary generalized glucocorticoid resistance and hypersensitivity.Semantic proximity Read ↗

Disease- and treatment-associated acquired glucocorticoid resistanceSemantic proximity Read ↗

Glucocorticoid Resistance: Interference between the Glucocorticoid Receptor and the MAPK Signalling Pathways.Semantic proximity Read ↗

Glucocorticoid resistance.Semantic proximity Read ↗

Glucocorticoid sensitivity in health and disease.Semantic proximity Read ↗

Novel insights into the molecular mechanisms underlying generalized glucocorticoid resistance and hypersensitivity syndromesSemantic proximity Read ↗

Mechanisms and resistance in glucocorticoid control of inflammationSemantic proximity Read ↗

Familial/sporadic glucocorticoid resistance: clinical phenotype and molecular mechanisms.Semantic proximity Read ↗

Novel causes of generalized glucocorticoid resistance.Semantic proximity Read ↗

Molecular mechanisms of glucocorticoid resistance.Semantic proximity Read ↗

Primary Generalized Glucocorticoid Resistance and Hypersensitivity Syndromes: A 2021 UpdateSemantic proximity Read ↗

Recent advances in the molecular mechanisms determining tissue sensitivity to glucocorticoids: novel mutations, circadian rhythm and ligand-induced repression of the human glucocorticoid receptor.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.