Article
Transcriptional control of the human glucocorticoid receptor: identification and analysis of alternative promoter regions.
Human genetics - 1 May 2011
Cao-Lei Lei, Leija Salomon Carlos, Kumsta Robert, Wüst Stefan, Meyer Jobst, Turner Jonathan D, Muller Claude P
Abstract excerpt
Glucocorticoid receptor levels are thought to be controlled by multiple alternative first exons. Seven of these exons are located in an upstream CpG island. In this study, we investigated the promoter activity of the intronic regions between these exons, and their susceptibility to CpG methylatio...
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