Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A spontaneous model for autoimmune myocarditis using the human MHC molecule HLA-DQ8.

Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2004

Taylor Jacqueline A, Havari Evis, McInerney Marcia F, Bronson Roderick, Wucherpfennig Kai W, Lipes Myra A

Abstract excerpt

Genome-wide analyses have shown that the MHC class II region is the principal locus that confers susceptibility to a number of human autoimmune diseases. Due to the high degree of linkage disequilibrium across the MHC, it has been difficult to dissect the contribution of individual genes to disea...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adoptive Transfer
Share to Autoimmune Diseases
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-DQ Antigens

Share to Immunoglobulin G

Share to Mice, Inbred NOD

Share to Myocarditis

Share to Spleen

Source

Identifiers

PMID: 14764740
DOI: 10.4049/jimmunol.172.4.2651

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14764740-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A spontaneous model for autoimmune myocarditis using the human MHC molecule HLA-DQ8.PMID 14764740Read ↗

CD4 T Cells Play Major Effector Role and CD8 T Cells Initiating Role in Spontaneous Autoimmune Myocarditis of HLA-DQ8 Transgenic IAb Knockout Nonobese Diabetic MiceSemantic proximity Read ↗

Generation of humanized mice susceptible to peptide-induced inflammatory heart disease.Semantic proximity Read ↗

Spontaneous autoimmune myocarditis and cardiomyopathy in HLA-DQ8.NODAbo transgenic miceSemantic proximity Read ↗

Human Leukocyte Antigen Determinants in Myocarditis and Dilated Cardiomyopathy.Semantic proximity Read ↗

[Autoimmune-associated MHC class II molecules].Semantic proximity Read ↗

HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic MiceSemantic proximity Read ↗

Humanized transgenic mice expressing HLA DR4-DQ3 haplotype: reconstitution of phenotype and HLA-restricted T-cell responses.Semantic proximity Read ↗

Autoimmune cardiac-specific T cell responses in dilated cardiomyopathy.Semantic proximity Read ↗

MHC class II molecules play a role in the selection of autoreactive class I-restricted CD8 T cells that are essential contributors to type 1 diabetes development in nonobese diabetic mice.Semantic proximity Read ↗

Identification of a novel cardiac epitope triggering T-cell responses in patients with myocardial infarctionSemantic proximity Read ↗

Homing of GAD65 specific autoimmunity and development of insulitis requires expression of both DQ8 and human GAD65 in transgenic mice.Semantic proximity Read ↗

Autoimmunity in heart disease: mechanisms and genetic susceptibility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.