Article
[Autoimmune-associated MHC class II molecules].
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - 1 Apr 1995
Trüeb M
Abstract excerpt
The major histocompatibility complex (MHC) is a large region of highly polymorphic genes. MHC-encoded molecules bind foreign-protein antigens and form complexes that are recognized by antigen-specific T lymphocytes. Interactions between MHC-peptide complexes and T-cell receptors play a central role in the selection of the T-cell repertoire and in the elicitation of an immune response. The majority of disease...
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