Article
Human Leukocyte Antigen Determinants in Myocarditis and Dilated Cardiomyopathy.
Current heart failure reports - 24 Apr 2026
Goli Nihit, Wilcox Jennifer, Barnard John, Tang W H Wilson
Abstract excerpt
PURPOSE OF REVIEW: Myocarditis, defined as inflammation of heart muscle, can be triggered by viral infection or have an autoimmune origin. In some cases, it progresses to dilated cardiomyopathy (DCM) and heart failure. The human leukocyte antigen (HLA) system is important in adaptive immunity by influencing antigen presentation and autoimmunity. This review intends to clarify the role of HLA polymorphisms in the...
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