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Article

Identification of a novel cardiac epitope triggering T-cell responses in patients with myocardial infarction

16 Sept 2022

Abstract excerpt

T-cells contribute to pathophysiological processes in myocardial diseases, including myocardial infarction (MI) and heart failure (HF). Antigen-specificity is a hallmark of T-cell responses but the cardiac antigens that trigger heart-directed T-cell responses in patients have not yet been uncovered, thus posing a roadblock to translation. In the present exploratory study, we identified a peptide fragment of the...

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PMID: 36122767
DOI: 10.1016/j.yjmcc.2022.09.001

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