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Article

Patent ductus venosus and dioxin resistance in mice harboring a hypomorphic Arnt allele.

The Journal of biological chemistry - 16 Apr 2004

Walisser Jacqueline A, Bunger Maureen K, Glover Edward, Harstad Eric B, Bradfield Christopher A

Abstract excerpt

The Ah receptor nuclear translocator (ARNT) is the dimeric partner of hypoxia-inducible factors and thus plays a pivotal role in cellular adaptation to low oxygen environments. ARNT is also a dimeric partner for the Ah receptor (AHR), and this complex is essential in regulating the adaptive metabolic response to polycyclic aromatic hydrocarbons. Because of the essential role of ARNT in hypoxia-driven...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14764592
DOI: 10.1074/jbc.M400784200

Genes

ARNT
AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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