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Article

Aryl hydrocarbon receptor-dependent liver development and hepatotoxicity are mediated by different cell types.

Proceedings of the National Academy of Sciences of the United States of America - 6 Dec 2005

Walisser Jacqueline A, Glover Edward, Pande Kalyan, Liss Adam L, Bradfield Christopher A

Abstract excerpt

The aryl hydrocarbon receptor (AHR) plays a role in three areas of biology that include the adaptive metabolism of xenobiotics, the toxic responses associated with exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (dioxin), and vascular remodeling of the developing embryo. To test the hypothesis that receptor signaling in different cell types is responsible for these aspects of AHR biology, we generated a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16301529
DOI: 10.1073/pnas.0504757102
PMCID: PMC1308889

Genes

AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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