Article
Lack of the Toll-Like Receptor 4 Gene Polymorphisms Asp299Gly and Thr399ile in a Chinese Population.
The International journal of neuroscience - 1 Jun 2010
Yuan Mei, Xia Jian, Ma Lin, Xiao Bo, Yang Qidong
Abstract excerpt
The toll-like receptor 4 (TLR4), predominantly known for its role as an important mediator of immune reactions, is expressed in atherosclerotic lesions. Atherosclerosis resulting in cerebral or carotid arterial stenosis/occlusion plays the most important role in the occurrence of cerebral infarction (CI), and thus TLR4 polymorphisms may influence formation of atherosclerosis and the development of CI. This study...
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