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Article

The Asp299Gly Toll-like receptor 4 polymorphism in advanced aortic atherosclerosis.

The Netherlands journal of medicine - 1 Jun 2007

Hommels M J, Kroon A A, Netea M G, de Leeuw P W, Bruggeman C A, Leiner T, Koster D A, Stalenhoef A F H, van der Ven A J A M

Abstract excerpt

BACKGROUND: Recently, the common Asp299Gly polymorphism of the Toll-like receptor 4 (TLR-4) was found to be associated with a reduced incidence of acute myocardial infarction and carotid atherosclerosis. As TLR-4 signalling is causally involved in atherogenesis, the polymorphism was postulated to...

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Identifiers

PMID: 17587646

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17587646-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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The Asp299Gly Toll-like receptor 4 polymorphism in advanced aortic atherosclerosis.PMID 17587646Read ↗

Lack of association between TLR4 Asp299Gly polymorphism and atherosclerosis: evidence from meta-analysis.Semantic proximity Read ↗

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Association of the Toll-like receptor 4 gene Asp299Gly polymorphism with acute coronary events.Semantic proximity Read ↗

Association studies of gene polymorphisms in toll-like receptors 2 and 4 in Croatian patients with acute myocardial infarction.Semantic proximity Read ↗

Association between Toll-like receptor 4 Asp299Gly polymorphism and coronary heart disease susceptibility.Semantic proximity Read ↗

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Toll-like receptor 4 gene Asp299Gly polymorphism in myocardial infarction: a meta-analysis of 15,148 subjects.Semantic proximity Read ↗

The functional Toll-like receptor 4 Asp299Gly polymorphism is associated with lower left ventricular mass in hypertensive women.Semantic proximity Read ↗

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