Article
In vivo regulation of growth hormone-stimulated gene transcription by STAT5b
3 Feb 2004
Abstract excerpt
The long-term effects of growth hormone (GH) are mediated through coordinated changes in gene expression that are the outcome of interactions between hormone-activated signal transduction pathways and specific feedback loops. Recent studies in mice have implicated the transcription factor STAT5b as part of the GH-regulated somatic growth pathway, because mice lacking this protein showed diminished growth rates....
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