Article
Pulmonary neoplasms in rats that inhaled cerium-144 dioxide.
Toxicologic pathology - 1 Jan 1992
Hahn F F, Lundgren D L
Abstract excerpt
The lung neoplasms induced in rats by inhaled, internally deposited 144CeO2 were described and classified using histologic criteria. F344 rats were exposed once or repeatedly by inhalation to 144CeO2 and observed for their life span. There was significant life shortening only in those rats with the highest radiation doses. In these rats, there was a high percentage of squamous cell carcinomas of the lung, as well...
Topics
- Adenocarcinoma
- Adenoma
- Administration, Inhalation
- Animals
- Carcinoma, Squamous Cell
- Cerium
- Cerium Radioisotopes
- Dose-Response Relationship, Radiation
- Female
- Hemangiosarcoma
- Lung Neoplasms
- Male
