Article
K-ras mutations in 239PuO2 canine lung neoplasms.
Cancer letters - 23 Oct 1998
Griffey S M, Kraegel S A, Weller R E, Watson C R, Madewell B R
Abstract excerpt
Single-strand conformational polymorphism (SSCP) analysis and direct sequencing methods were used to examine lung tumors derived from a cohort of beagle dogs with inhalational exposures to 239PuO2. These exposures were done at Pacific Northwest Laboratories where 18-month-old beagle dogs were given 239PuO2 by single-dose inhalation and allowed to live out their life-spans. Formalin-fixed paraffin-embedded blocks...
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